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Spike in Harm to Liver Is Tied to Dietary Supplements4
HSVG misson P.O. Box 206, Hagatna, GU 96932, USA
(01/17/2022)Did G20 learn lessons from the Delta? When the world welcomed 2022, many people were actually calling the new year “pandemic year 3.” If we have had it enough and do not want “pandemic year 4,” year 5 or year 6, let’s encourage Indonesian government step forward with its Group of 20 (G20) presidency to call for an international campaign helping people around the globe fearlessly live with the coronavirus and adopt the new normal as soon as possible. Quite a number of public health experts had advised before COVID vaccines became available that the human society was inevitably going to live with the coronavirus for a while and only sustainable measures would help everybody get through the pandemic. Unfortunately, most governments , with certain high-profile scientists and celebrities, put so much faith in lockdowns and looked forward to seeing COVID vaccines would work perfectly like a silver bullet even though, at that time, almost every vaccine developer was apparently targeting at lowering the numbers of severe patients and death victims instead of guaranteeing no infections after getting vaccinated. The Delta variant’s attack last summer was a wake-up call. Many countries, after enjoying reopening and sort of returning to normal brought by successful vaccine rollouts, experienced the Delta variant of the coronavirus caused a new wave of case surge, made hospitals overwhelmed again, and, sadly, took many people’s lives. It was the time that people started being familiar with a term called “breakthrough infections.” For example, Singapore surprisingly reported 28,901 new infections and 40 deaths in September 2021 after the vaccination rate was beyond 80%. Their COVID death number was zero in September 2020 when there was no CIVID vaccine at all. The epidemiological investigation and laboratory results concluded the changed situation was mainly caused by the Delta variant. Singapore was not the only place having a bad September last year. As of 31 August 2021, 80.43% of the residents 12 years and older were fully vaccinated, but Guam, an US island territory in the Pacific reported 47 COVID-related fatalities in September 2021. The figure was higher than the death number of 39 reported in September 2020 when no vaccine was available at that time. With almost the same land size, Guam is home of less than 200 thousand residents and Singapore has a population of 5.7 million. It means the highly-contagious Delta variant was influencing everywhere, no matter a busy and crowded city or a relaxed and rural place. In addition, obviously, vaccines alone are not suppressing the coronavirus. Europe’s experience reminded that nobody should drop his/her guard even thought the population reached a high vaccination rate. European Union has been leading its member states to keep precautions and try reopening in a gradual way. The continent has maintained a basically downward curve of infections as well as hospitalizations and deaths since its successful vaccine rollouts in association with well-managed medical capacity, even though the Delta variant did make a noticeable, but not really harmful, spike. However, it seemed that most parts of the world did not learn lessons from the Delta and implement proper measures when the Omicron came. The World Health Organization did not wait for sufficient morbidity and fatality data to be collected. Its warning message on the Omicron variant released late November last year triggered many countries’ panicked decisions of tightening COVID restrictions. It’s sad that South Africa’s variant identification efforts, which should have been appreciated, made its people punished by the almost worldwide travel ban. The wait wasn’t even long. Before last Christmas, at least three scientific researches caught the media’s attention and proved the Omicron variant may be much more contagious but it’s mostly causing mild cases. However, the chaos has hurt people. For example, Guam, which finally saw a little bit tourism recovery last November, immediately suffered from more than 5000 travel booking cancellations right after the Omicron panic widely spread. More variants will definitely come and we definitely do not want more chaos. While the Omicron has shown the new variants in the future are very likely to be less lethal and the COVID vaccines are actually promisingly reducing severe cases, plus the antiviral medicines are available, the whole world really needs a leadership that urges every jurisdiction to guide people fearlessly living with the virus by using more appropriate strategies to respond to every emerging variant. Let’s try to recall whether the system was encouraging people to get tested during the flu season to try to contain flu viruses. Were we worried so much when we experienced flu-like symptoms or got diagnosed as having flu? Wasn’t the goal of flu control to avoid severe complications and save people’s lives? The best tools helping us achieve the goal are always personal hygiene and flu vaccines although so-called “breakthrough infections” did happen to flu vaccines as well. COVID is not flu, but flu control experience could apply to COVID response, especially to the current situation of “pandemic year 3,” a year that G20 presidency returns to Asia, where people totally have no issue with wearing a mask and helped prove this measure could effectively prevent COVID spread. Indonesian government needs to work with its G20 partners and make history.(Published in The Jakarta Post on January 11, 2022) http://www.hsvg.org/hot_414422.html Did G20 learn lessons from Delta variant? 2022-01-17 2023-01-17
HSVG misson P.O. Box 206, Hagatna, GU 96932, USA http://www.hsvg.org/hot_414422.html
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Links:http://www.nytimes.com/2013/12/22/us/spike-in-harm-to-liver- ...

The New York Times reported that dietary supplements account for nearly 20 percent of drug-related liver injuries that turn up in hospitals, up from 7 percent a decade ago, according to an analysis by a national network of liver specialists.

The new research, presented at a conference in Washington in November 2013, was produced by the Drug-Induced Liver Injury Network, which was established by the National Institutes of Health to track patients who suffer liver damage from certain drugs and alternative medicines. It includes doctors at eight major hospitals throughout the country. When the network began tracking liver injuries in 2004, supplements accounted for 7 percent of the 115 severe cases. But the percentage has steadily risen, reaching 20 percent of the 313 cases recorded from 2010 to 2012.

The report emphasized that the research included only the most severe cases of liver damage referred to a representative group of hospitals around the country, and the investigators said they were undercounting the actual number of cases.

Those patients included dozens of young men who were sickened by bodybuilding supplements.  Tests showed that a third of the implicated products contained steroids not listed on their labels.

 

A second trend emerged when the investigators studied 85 patients with liver injuries linked to herbal pills and powders. Two-thirds were middle-aged women, on average 48 years old, who often used the supplements to lose weight or increase energy. Nearly a dozen of those patients required liver transplants, and three died.

 

One product that patients used frequently was green tea extract, which contains catechins, a group of potent antioxidants that reputedly increase metabolism. The extracts are often marketed as fat burners, and catechins are often added to weight-loss products and energy boosters. Most green tea pills are highly concentrated, containing many times the amount of catechins found in a single cup of green tea, Dr. Bonkovsky,  an investigator with the network, said. In high doses, catechins can be toxic to the liver, he said, and a small percentage of people appear to be particularly susceptible.

The New York Time article also said that Americans spend an estimated $32 billion on dietary supplements every year, attracted by unproven claims that various pills and powders will help them lose weight, build muscle and fight off everything from colds to chronic illnesses. About half of Americans use dietary supplements, and most of them take more than one product at a time. But the supplement business is largely unregulated. In recent years, critics of the industry have called for measures that would force companies to prove that their products are safe, genuine and made in accordance with strict manufacturing standards before they reach the market.

However, the article added that a federal law enacted in 1994, the Dietary Supplement Health and Education Act, prevents the Food and Drug Administration from approving or evaluating most supplements before they are sold. Usually the agency must wait until consumers are harmed before officials can remove products from stores. Because the supplement industry operates on the honor system, studies show, the market has been flooded with products that are adulterated, mislabeled or packaged in dosages that have not been studied for safety.

Since 2008, the F.D.A. has been taking action against companies whose supplements are found to contain prescription drugs and controlled substances, said Daniel Fabricant, the director of the division of dietary supplement programs in the agency’s Center for Food Safety and Applied Nutrition. For example, the agency recently took steps to remove one “fat burning” product from shelves, OxyElite Pro, that was linked to one death and dozens of cases of hepatitis and liver injury in Hawaii and other states.

 

HSVG wholesome would like to take this opportunity to remind vitamin shoppers to take a look at our webpage www.hsvg.org/hot_cg1990.html to see which brands and products are in the list of HSVG wholesome certification. The certified brands and products were reviewed carefully and were ensured safe and of good quality by HSVG wholesome.